Hematological analysis process 2 (ILV)

Course numberB3.06651.30.380
Course codeHämaAP2
Semester of degree program Semester 3
Mode of delivery Presencecourse
ECTS credits3,0
Language of instruction German

Based on an understanding of the physiological and pathophysiological regulatory mechanisms of hematopoiesis and the immune system and based on a doctor's order, students are able to independently carry out the biomedical analysis process (pre-analytical, analytical and post-analytical phases) in hematology / hematopathology as part of the medical overall process. They i.e.:

  • Can assign the relevant measures to the bioanalytical and medical questions, can understand the reasoning for those measures and judge the quality of the material at hands
  • Know the preanalytical influencing and method-dependent disturbance variables for the respective measured quantities and their effects on the respective laboratory examination
  • Can select, critically assess and evaluate the hematological analysis methods according to the question
  • Know the basic reaction processes in the analysis process and recognize them in the automated processes
  • Based on their knowledge of the measuring process, evaluation, method-specific measured values, measurement results and calculation methods, they can relate to methods of data acquisition (for example, histograms and scattergrams of blood pictures) and relate them to the functionality of current and new device technologies
  • Independently choose the right steps and measures in the analytical process and apply selected hematological analysis (particle counts, differential blood counts, immunophenotyping) to different sample materials using appropriate measurement, detection and assessment methods based on manuals
  • Are able to coordinate work processes and to schedule them efficiently
  • Can independently carry out and assess the subject-specific quality assurance measures
  • Can identify simple mistakes in the implementation of a method, allocate them correctly and remedy them as far as possible
  • Can document the study results with existing information technologies
  • Are able to microscopically describe elements in blood smear preparations and bone marrow specimens according to current nomenclature, to differentiate blood smears and to assign them to the microscopic image according to a hematological disorder
  • Are able to technically and biomedically validate results, to assess their significance for clinical diagnostics and to - taking the patient into account - connect the various hematological / hematopathological findings, place them in an overall picture and be aware of its consequences for the patient
  • Can, based on the available laboratory results, logically select further laboratory analysis (step-by-step diagnostics) Know about the manufacture and use of blood products and they know about the need to track current developments and integrate them into their work

Modules of the 1st and 2nd semester

  • Evaluation and assessment of automated blood counts with respect to deviations / pathologies including interpretation of the graphs (histograms, scattergrams)
  • Special dyeing techniques - execution and interpretation
  • Disorders in hematopoiesis, hematopoietic neoplasms and their microscopic description and differentiation (myelogram) including interpretation (pathological differential blood counts including selected bone marrow preparations)
  • Technical and biomedical validation of hematological laboratory results
  • Advanced hematological laboratory diagnostics, special questions

Mahlberg R. et al. (2014), Hämatologie: Theorie und Praxis für medizinische Assistenzberufe, VCH Verlag;
Hallbach J. (2019), Klinische Chemie und Hämatologie: Biomedizinische Analytik für MTLA und Studium, Thieme;
Haferlach T. et al. (2019), Taschenatlas Hämatologie: Mikroskopische und klinische Diagnostik für die Praxis, Thieme;
Freund M. (2008), Praktikum der mikroskopischen Hämatologie: Begründet von Fritz Heckner, Elsevier;
Moore G. et al. (2016) Haematology, Oxford New York: Oxford University Press;
Fangerau H. et al. (2014), Medizinische Terminologie - ein Kompaktkurs, Lehmanns Media;
Michl M. (2016), Hämatologie - Basics, Elsevier;
Books, journals and websites according to the current state of knowledge in the respective fields.

Lectures, demonstrations, laboratory exercises, discussions